#47 Hidden Risks of PGT-A Testing in IVF and Surrogacy - Allison Freeman

    Episode Notes

    PGT-A testing is marketed as a smart, science-backed way to improve your chances of a healthy baby. But what if it’s not giving you the full story?

    In this eye-opening conversation, fertility attorney and IVF mom Allison Freeman joins Alyssa to unpack the science, marketing, and legal implications behind preimplantation genetic testing for aneuploidy (PGT-A).

    From personal IVF loss to class-action lawsuits, Allison shares why more patients are questioning the test—and why some may be discarding embryos based on misleading or unvalidated results.

    🎧 If you’re considering embryo testing—or already making transfer decisions—this episode is a must-listen.

    What You’ll Learn:

    • 02:16 — Allison’s IVF journey and two very different paths to motherhood

    • 09:08 — How a personal red flag during IUI launched her legal advocacy

    • 16:24 — What PGT-A testing is, and how it’s commonly presented to patients

    • 19:04 — The rise in “zero embryos” after testing—and what that might mean

    • 21:55 — Why PGT-A biopsies aren’t as definitive as many think

    • 26:27 — The risks of relying on embryo testing to avoid miscarriage

    • 29:46 — How PGT-A impacts surrogacy matching and timeline delays

    • 34:54 — What ASRM’s new guidance really says—and what patients often miss

    Resources Mentioned:


  1. Key Takeaways:

    • PGT-A is widely used—but hasn’t been validated the way most patients expect

    • The test analyzes placental (not fetal) tissue, which can cause discrepancies

    • Surrogates and agencies often require PGT-A without understanding its limitations

    • Patients should ask: what am I being promised, and is there data to back it up?


    🎧 Considering embryo testing? With ASRM’s most recent guidance, and the BloomBridge surrogacy app you'll be prepared for tough decisions.

    About Dr. Alyssa Small Layne

    Dr. Alyssa Small Layne is a board-certified OB/GYN and minimally invasive gynecologic surgeon with extensive experience in surrogate requirements and gestational carrier support. After navigating her own surrogacy journey as an intended parent, she founded JUNIE to provide comprehensive surrogacy guidance and support.

    On Surrogacy Made Simple, Dr. Layne combines her medical expertise with personal experience to help intended parents and surrogates navigate the surrogacy process with confidence and clarity.

    Episode Information

    Episode:#47
    Duration:00:36:51
    Published:6/19/2025
    Guest:Allison Freeman

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